The play is based on the life of the real Louis de Bussy d'Amboise, who was murdered in 1579.
This edition of George Chapman's tragedy differs from all other modern editions in being based primarily on the Quarto of 1607 in preference to the much revised Quarto of 1641.
"The Revenge of Bussy D'Ambois" continues the story as Bussy seeks vengeance for the betrayal and murder of his beloved.